3029936-02-2
Chemical Structure
LASSBio-1632
- CAS No.: 3029936-02-2
- Formula:C18H20N2O6S
- Molecular Weight:392.43
IUPAC Name: (E)-N'-(3,4-dimethoxybenzylidene)-N,6-dimethylbenzo[d][1,3]dioxole-5-sulfonohydrazide
InChIKey: NZSOVSBBNFQRLT-VXLYETTFSA-N
SMILES: CC1=CC2=C(C=C1S(N(/N=C/C3=CC=C(C(OC)=C3)OC)C)(=O)=O)OCO2
Biological Activity: LASSBio-1632 is a new anti-asthmatic lead candidate associated with selective inhibition of PDE4A and PDE4D isoenzymes and blockade of airway hyper-reactivity (AHR) and TNF-α production in the lung tissue. LASSBio-1632 (7j) displays high experimental BBB permeability across BBB through passive diffusion[1].
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LASSBio-1632 | LASSBio-1632 is a new anti-asthmatic lead candidate associated with selective inhibition of PDE4A and PDE4D isoenzymes and blockade of airway hyper-reactivity (AHR) and TNF-α production in the lung tissue. LASSBio-1632 (7j) displays high experimental BBB permeability across BBB through passive diffusion. | |||||||||||||||||||||
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Keywords