3034595-62-2
3034595-62-2
Chemical Structure
P300-IN-6
- CAS No.: 3034595-62-2
- Formula:C26H26N6O2
- Molecular Weight:454.52
InChIKey: JLYBAYYSYHDBBZ-UZUQRXQVSA-N
SMILES: CN1C2=CC=C(NC([C@@H](C3=CC=CC=C3)NC[C@@H](C)C4=CC=C(C#N)C=C4)=O)N=C2N(C)C1=O
Biological Activity: P300-IN-6 is an orally active histone acetyltransferase p300 HAT domain inhibitor with human IC50 values of 7 nM. P300-IN-6 suppresses c-Myc expression, decreases H3K18ac and H3K27ac levels, and inhibits cancer cell proliferation.P300-IN-6 suppresses tumor growth in xenograft mouse models.P300-IN-6 can be used for the research of multiple myeloma[1].
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P300-IN-6 | P300-IN-6 is an orally active histone acetyltransferase p300 HAT domain inhibitor with human IC50 values of 7 nM. P300-IN-6 suppresses c-Myc expression, decreases H3K18ac and H3K27ac levels, and inhibits cancer cell proliferation.P300-IN-6 suppresses tumor growth in xenograft mouse models.P300-IN-6 can be used for the research of multiple myeloma. | |||||||||||||||||||||
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References
Keywords
