3034696-13-1
3034696-13-1
Chemical Structure
S-HP210
- CAS No.: 3034696-13-1
- Formula:C22H19N3O2S2
- Molecular Weight:421.54
InChIKey: AJJBGZJAGZSMJI-AWEZNQCLSA-N
SMILES: C[C@@H](C1=CC=CC=C1)NC(C2=CC=C(C=C2)CN3C(C4=C(NC3=S)C=CS4)=O)=O
Biological Activity: S-HP210 is a potent and selective glucocorticoid receptor (GR) with an IC50 value of 1.92 μM for NF-κB transrepression (TR). S-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1β, IL-6 and COX-2. S-HP210 is nontoxic at effective doses against mouse fibroblasts 3T3 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S-HP210 | 98.12% | S-HP210 is a potent and selective glucocorticoid receptor (GR) with an IC50 value of 1.92 μM for NF-κB transrepression (TR). S-HP210 represses the LPS-induced transcription of a variety of proinflammatory genes such as IL-1β, IL-6 and COX-2. S-HP210 is nontoxic at effective doses against mouse fibroblasts 3T3 cells. | ||||||||||||||||||||
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References
Keywords
