3034764-41-2
3034764-41-2
Chemical Structure
GSPT1 degrader-6
- CAS No.: 3034764-41-2
- Formula:C24H22ClN5O5
- Molecular Weight:495.91
InChIKey: DQJUDOPJKAMACO-UHFFFAOYSA-N
SMILES: ClC1=CC(NC(OCC2=CC=C3C(C=C(CN4C5C(NC(CC5)=O)=O)N3C4=O)=C2)=O)=CC=C1NC
Biological Activity: GSPT1 degrader-6 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 13 nM. GSPT1 degrader-6 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-6 can be used in breast cancer-related research[1].
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GSPT1 degrader-6 | GSPT1 degrader-6 is a GSPT1 molecular glue degrader that recruits cereblon (CRBN), with a DC50 of 13 nM. GSPT1 degrader-6 induces GSPT1 protein degradation via the ubiquitin-proteasome pathway. GSPT1 degrader-6 can be used in breast cancer-related research. | |||||||||||||||||||||
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