3034840-19-9
Chemical Structure
M4K2281
- CAS No.: 3034840-19-9
- Formula:C27H31N3O4
- Molecular Weight:461.55
InChIKey: MMQQLUARMBFVKE-UHFFFAOYSA-N
SMILES: CN1CCN(CC1)C2=CC=C3C(OCCC4=C3C=NC=C4C5=CC(OC)=C(C(OC)=C5)OC)=C2
Biological Activity: M4K2281 is a selecitve inhibitor for activin receptor-like kinase-2 (ALK2) with an IC50 of 2 nM. M4K2281 exhibits a moderate blood brain permeability with a brain to plasma ratio of 3.7 at 4h[1].
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M4K2281 | M4K2281 is a selecitve inhibitor for activin receptor-like kinase-2 (ALK2) with an IC50 of 2 nM. M4K2281 exhibits a moderate blood brain permeability with a brain to plasma ratio of 3.7 at 4h. | |||||||||||||||||||||
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Keywords