M4K2281
M4K2281 is a selecitve inhibitor for activin receptor-like kinase-2 (ALK2) with an IC50 of 2 nM. M4K2281 exhibits a moderate blood brain permeability with a brain to plasma ratio of 3.7 at 4h.
For research use only. We do not sell to patients.
- CAS No.: 3034840-19-9
- Formula: C27H31N3O4
- Molecular Weight:461.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ALK2 2 nM (IC50) |
ALK5 350 nM (IC50) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3034840-19-9
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Molecular Weight 461.55
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Formula C27H31N3O4
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SMILES
CN1CCN(CC1)C2=CC=C3C(OCCC4=C3C=NC=C4C5=CC(OC)=C(C(OC)=C5)OC)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)