3040120-71-3
Chemical Structure
CBP/p300 ligand 4
- CAS No.: 3040120-71-3
- Formula:C30H31F2N5O4
- Molecular Weight:563.60
InChIKey: BVLKHFWDLAGSMY-SANMLTNESA-N
SMILES: O=C1CCC[C@H](N1C2=CC=C(C(F)=C2)F)C3=NC4=C(C=CC(C5=C(ON=C5C)C)=C4)N3C6CCN(CC(O)=O)CC6
Biological Activity: CBP/p300 ligand 4 (Compound 4) is an orally active inhibitor for CBP/p300 bromodomain, with IC50 of 91.4 nM. CBP/p300 ligand 4 serves as a ligand for target protein XYD190 (HY-161495). XYD190 is a PROTAC degrader for CBP/p300[1].
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CBP/p300 ligand 4 | CBP/p300 ligand 4 (Compound 4) is an orally active inhibitor for CBP/p300 bromodomain, with IC50 of 91.4 nM. CBP/p300 ligand 4 serves as a ligand for target protein XYD190 (HY-161495). XYD190 is a PROTAC degrader for CBP/p300. | |||||||||||||||||||||
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Keywords