3040999-70-7
3040999-70-7
Chemical Structure
CDK7-IN-30
- CAS No.: 3040999-70-7
- Formula:C21H28ClN5O3S
- Molecular Weight:466.00
InChIKey: DEWMOHMMBPEEPV-WKILWMFISA-N
SMILES: CC(C)S(C(C=CC=C1)=C1NC2=NC(N[C@@H]3CC[C@H](CC3)NC(C)=O)=NC=C2Cl)(=O)=O
Biological Activity: CDK7-IN-30 (Compound 22) is a CDK7 inhibitor (IC50 = 7.21 nM) that effectively inhibits the phosphorylation of RNA Polymerase II and CDK2. CDK7-IN-30 CDK7-IN-30 can induce cell apoptosis and has anti-cancer activity and can be used in cancer research[1].
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CDK7-IN-30 | CDK7-IN-30 (Compound 22) is a CDK7 inhibitor (IC50 = 7.21 nM) that effectively inhibits the phosphorylation of RNA Polymerase II and CDK2. CDK7-IN-30 CDK7-IN-30 can induce cell apoptosis and has anti-cancer activity and can be used in cancer research. | |||||||||||||||||||||
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References
Keywords
