3044733-61-8
3044733-61-8
Chemical Structure
NDM-1-IN-10
- CAS No.: 3044733-61-8
- Formula:C18H11NaO6S3
- Molecular Weight:442.46
SMILES: O=S(C(C1=COC2=C(C=CC(SC3=CC4=CC=CC=C4S3)=C2)C1=O)O)(O[Na])=O
Biological Activity: NDM-1-IN-10 (Compound CS-23) is an irreversible and covalent New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 36 nM. NDM-1-IN-10 shows a synergistic effect with Meropenem (HY-13678) against NDM-1-expressing E. coli ( MIC of 0.25 μg/mL for E. coli BL21/pET15b-blaNDM-1). NDM-1-IN-10 can be used for bacterial infections research[1].
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NDM-1-IN-10 | NDM-1-IN-10 (Compound CS-23) is an irreversible and covalent New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with an IC50 of 36 nM. NDM-1-IN-10 shows a synergistic effect with Meropenem (HY-13678) against NDM-1-expressing E. coli ( MIC of 0.25 μg/mL for E. coli BL21/pET15b-blaNDM-1). NDM-1-IN-10 can be used for bacterial infections research. | |||||||||||||||||||||
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References
Keywords
