3047956-65-7
Chemical Structure
TRPC5-IN-6
- CAS No.: 3047956-65-7
- Formula:C18H16Cl2FN5O2
- Molecular Weight:424.26
InChIKey: BTYWGUNWQBPKKY-UHFFFAOYSA-N
SMILES: O=C1C(Cl)=C(N2CCN3C(C2)=NC=C3C(C4=C(Cl)C=C(F)C=C4)OC)C=NN1
Biological Activity: TRPC5-IN-6 (Compound 12) is an orally effective transient receptor potential (TRPC5) inhibitor with a IC50 value of 81 nM. TRPC5-IN-6 has good biosafety and low liver and kidney toxicity, and is expected to play an important role in the treatment of chronic kidney disease (CKD)[1].
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TRPC5-IN-6 | TRPC5-IN-6 (Compound 12) is an orally effective transient receptor potential (TRPC5) inhibitor with a IC50 value of 81 nM. TRPC5-IN-6 has good biosafety and low liver and kidney toxicity, and is expected to play an important role in the treatment of chronic kidney disease (CKD). | |||||||||||||||||||||
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Keywords