3048344-59-5
3048344-59-5
Chemical Structure
RORγt inverse agonist 31
- CAS No.: 3048344-59-5
- Formula:C23H15Cl2F3N4O3S
- Molecular Weight:555.36
InChIKey: SGNCATNWBIODJJ-UHFFFAOYSA-N
SMILES: FC(C1=CC=C(C2=NC(NC3=CC=C(S(=O)(C)=O)C=C3)=NC(OC4=C(Cl)C=CC=C4Cl)=N2)C=C1)(F)F
Biological Activity: RORγt inverse agonist 31 (14g) is a potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 0.428 μM. RORγt inverse agonist 31 can alleviate the severity of Imiquimod (HY-B0180)-induced psoriasis in mice[1].
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RORγt inverse agonist 31 | RORγt inverse agonist 31 (14g) is a potent retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonist, with an IC50 of 0.428 μM. RORγt inverse agonist 31 can alleviate the severity of Imiquimod (HY-B0180)-induced psoriasis in mice. | |||||||||||||||||||||
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