3049949-94-9

GPR34 receptor antagonist 3 Chemical Structure
3049949-94-9

Chemical Structure

GPR34 receptor antagonist 3

  • CAS No.: 3049949-94-9
  • Formula:C30H26ClNO5
  • Molecular Weight:515.98

InChIKey: PGLQPMIYELXADW-NDEPHWFRSA-N

SMILES: O=C(COC1=CC=C(C2=CC(Cl)=CC=C2)C=C1)N[C@H](C(O)=O)CC(C=C3)=CC=C3OCC4=CC=CC=C4

Biological Activity: GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680 μM. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model [1].

Cat. No. Product Name Purity Description Pricing
HY-155417
GPR34 receptor antagonist 3 99.88% GPR34 receptor antagonist 3 (Compound 5e) is a class of GRP34 antagonists, IC50 is 0.680 μM. GPR34 receptor antagonist 3 inhibited ERK1/2 phosphorylation induced by lysophosphatidylserine in a dose-dependent way without obvious cytotoxicity. GPR34 receptor antagonist 3 shows antisensory activity in mouse neuropathic pain model .
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