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GPR34 receptor antagonist 2 

Cat. No.: HY-138501
Handling Instructions

GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research.

For research use only. We do not sell to patients.

GPR34 receptor antagonist 2 Chemical Structure

GPR34 receptor antagonist 2 Chemical Structure

CAS No. : 907952-06-1

Size Price Stock Quantity
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1700 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
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Based on 1 publication(s) in Google Scholar

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Description

GPR34 receptor antagonist 2 (Compound D2) is a GPR34 receptor antagonist. GPR34 receptor antagonist 2 can be used for immune diseases, inflammatory diseases research[1].

IC50 & Target

GPR34 receptor[1]

In Vitro

Endogenous ligands of GPR34, a G protein-coupled receptor, act on histamine-releasing activity on antigen- or concanavalin A-stimulated rat mast cells and synergize with nerve growth factor on rat mast cells. It is a lipid such as lysophosphatidylserine having the activity of releasing histamine. GPR34 antagonists can be used, for example, for histamine release inhibitors, immune diseases, edema, hyperacidity, etc[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

512.00

Formula

C₃₁H₂₆ClNO₄

CAS No.

907952-06-1

SMILES

OC(C(CC1=CC=C(C=C1)OCC2=CC=CC=C2)NC(/C=C/C3=CC=C(C4=CC=C(C=C4)Cl)C=C3)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (162.75 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9531 mL 9.7656 mL 19.5312 mL
5 mM 0.3906 mL 1.9531 mL 3.9062 mL
10 mM 0.1953 mL 0.9766 mL 1.9531 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 2.08 mg/mL (4.06 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (4.06 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

GPR34 receptor antagonist 2OthersGPR34immuneinflammatoryInhibitorinhibitorinhibit

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Product Name:
GPR34 receptor antagonist 2
Cat. No.:
HY-138501
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