3050598-72-3
Chemical Structure
ICeD-2
- CAS No.: 3050598-72-3
- Formula:C20H29N3O
- Molecular Weight:327.46
IUPAC Name: (S)-2-amino-1-(isoindolin-2-yl)-2-((1r,4S)-4-(pyrrolidin-1-yl)cyclohexyl)ethan-1-one
InChIKey: SYXDQNGJEXFDND-SNRMKQJTSA-N
SMILES: O=C(N1CC(C=CC=C2)=C2C1)[C@@H](N)[C@@H](CC3)CC[C@H]3N4CCCC4
Biological Activity: ICeD-2 is a inducer of cell death, can induce HIV-1 infected cell kill. ICeD-2-mediated HIV-1 infected cell kill is dependent on HIV-1 protease activity. ICeD-2 potently blocks hydrolysis of Gly-Pro-AMC by dipeptidyl peptidase DPP8 and DPP9. ICeD-2 shows strong stabilization of DPP9 in PBMCs[1].
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ICeD-2 | ICeD-2 is a inducer of cell death, can induce HIV-1 infected cell kill. ICeD-2-mediated HIV-1 infected cell kill is dependent on HIV-1 protease activity. ICeD-2 potently blocks hydrolysis of Gly-Pro-AMC by dipeptidyl peptidase DPP8 and DPP9. ICeD-2 shows strong stabilization of DPP9 in PBMCs. | |||||||||||||||||||||
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Keywords
