3058433-50-1
3058433-50-1
Chemical Structure
MLL1-IN-1
- CAS No.: 3058433-50-1
- Formula:C34H44FN5O3
- Molecular Weight:589.74
InChIKey: SVCCZXAYHYYWPC-MHZLTWQESA-N
SMILES: FC1=CC=[C@]([N@]2C(C=NC=C3)=C3C(C(C4CCN(C([C@@H]5CCC(C)(C)N5)=O)CC4)=O)=C2C)C(C(N(C(C)C)C(C)C)=O)=C1
Biological Activity: MLL1-IN-1 is an orally active MLL1 inhibitor with an IC50 of 0.043 μM. MLL1-IN-1 induces Menin protein degradation and inhibits the proliferation of leukemia cells. MLL1-IN-1 can induce tumor regression in leukemia-bearing mice. MLL1-IN-1 is useful for research into MLL1-associated leukemia[1].
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MLL1-IN-1 | MLL1-IN-1 is an orally active MLL1 inhibitor with an IC50 of 0.043 μM. MLL1-IN-1 induces Menin protein degradation and inhibits the proliferation of leukemia cells. MLL1-IN-1 can induce tumor regression in leukemia-bearing mice. MLL1-IN-1 is useful for research into MLL1-associated leukemia. | |||||||||||||||||||||
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References
Keywords
