3059767-85-7
3059767-85-7
Chemical Structure
HEAL-116
- CAS No.: 3059767-85-7
- Formula:C20H18ClNO4
- Molecular Weight:371.81
SMILES: OC1=CC(OC=C(C2=CC=C(Cl)C(CN3CCOCC3)=C2)C4=O)=C4C=C1
Biological Activity: HEAL-116 is a potent, specific and orally active 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor with an IC50 of 1.18 μM and a KD of 1.32 μM. HEAL-116 inhibits DHEA (HY-14650) metabolism and DHEA-induced target gene expression and cell proliferation. HEAL-116 can be used for cancer research, such as prostate cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HEAL-116 | 98.52% | HEAL-116 is a potent, specific and orally active 3β-hydroxysteroid dehydrogenase type 1 (3βHSD1) inhibitor with an IC50 of 1.18 μM and a KD of 1.32 μM. HEAL-116 inhibits DHEA (HY-14650) metabolism and DHEA-induced target gene expression and cell proliferation. HEAL-116 can be used for cancer research, such as prostate cancer. | ||||||||||||||||||||
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References
Keywords
