3061559-97-2
3061559-97-2
Chemical Structure
KARI 101
- CAS No.: 3061559-97-2
- Formula:C15H30N4O2
- Molecular Weight:298.42
InChIKey: VMHYPRRZWPKMFJ-UHFFFAOYSA-N
SMILES: OCC(C1=CN(CCCCCCCCCC)N=N1)(CO)N
Biological Activity: KARI 101 is a blood-brain barrier permeable acid sphingomyelinase (ASM) inhibitor. KARI 101 directly inhibits ASM activity and reduces ceramide production. KARI 101 induces Ca2+ mobilization, activates AMPK and triggers GHSR1α internalization. KARI 101 can be used for the research of Alzheimer's disease[1].
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KARI 101 | KARI 101 is a blood-brain barrier permeable acid sphingomyelinase (ASM) inhibitor. KARI 101 directly inhibits ASM activity and reduces ceramide production. KARI 101 induces Ca2+ mobilization, activates AMPK and triggers GHSR1α internalization. KARI 101 can be used for the research of Alzheimer's disease. | |||||||||||||||||||||
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