3066798-40-8
3066798-40-8
Chemical Structure
PARP1-IN-43
- CAS No.: 3066798-40-8
- Formula:C29H30N4O5
- Molecular Weight:514.57
SMILES: CC(N1CCCC(C1)C(N2CCN(CC2)C(C3=CC4=C(C(C5=C6CNC(C6=CC=C5)=O)=CC=C4)O3)=O)=O)=O
Biological Activity: PARP1-IN-43 (Compound 5350) is a blood-brain barrier (BBB) permeable PARP1 inhibitor, with an IC50 of 5 nM. PARP1-IN-43 can be used for the study of homologous recombination (HR)-deficient central nerve system (CNS) cancers[1].
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PARP1-IN-43 | PARP1-IN-43 (Compound 5350) is a blood-brain barrier (BBB) permeable PARP1 inhibitor, with an IC50 of 5 nM. PARP1-IN-43 can be used for the study of homologous recombination (HR)-deficient central nerve system (CNS) cancers. | |||||||||||||||||||||
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