3068162-16-0
3068162-16-0
Chemical Structure
PROTAC HDAC6 degrader 6
- CAS No.: 3068162-16-0
- Formula:C41H48N8O11
- Molecular Weight:828.87
InChIKey: JFUQCXOUDYXHML-CPHIHMHPSA-N
SMILES: COC(C=C1/N=N/C2=C3C(C(N(C4C(NC(CC4)=O)=O)C3)=O)=CC=C2)=C(C(OC)=C1)OCC(NCCCC(NC5=CC=C(C=C5)C(NCCCCCCC(NO)=O)=O)=O)=O
Biological Activity: PROTAC HDAC6 degrader 6 (Compound 12) is a selective HDAC6-targeting photochemically targeting chimeras (PHOTACs) (subset of PROTAC) degrader with a ～50% Dmax only upon activation to its cis-state with 390 nm light irradiation[1].
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PROTAC HDAC6 degrader 6 | PROTAC HDAC6 degrader 6 (Compound 12) is a selective HDAC6-targeting photochemically targeting chimeras (PHOTACs) (subset of PROTAC) degrader with a ～50% Dmax only upon activation to its cis-state with 390 nm light irradiation. | |||||||||||||||||||||
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References
Keywords
