3069916-11-3
3069916-11-3
Chemical Structure
Xanthine oxidase-IN-20
- CAS. Nr.: 3069916-11-3
- Formula:C21H22N6O6
- Molecular Weight:454.44
InChIKey: KCWARMQRBSJHJY-VNTMZGSJSA-N
SMILES: OC(C1=CN(C2=CC=C(C(N3N=NN=C3)=C2)O[C@H]4CO[C@]5([C@@]4(OC[C@@H]5OCC(C)=C)[H])[H])N=C1)=O
Biological Activity: Xanthine oxidase-IN-20 is a potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 1.7 nM. Xanthine oxidase-IN-20 exhibits outstanding serum uric acid (SUA)-lowering efficacy in both mouse and rat acute hyperuricemia models. Xanthine oxidase-IN-20 shows favorable safety profile. Xanthine oxidase-IN-20 can be used for hyperuricemia and gout research[1].
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Xanthine oxidase-IN-20 | Xanthine oxidase-IN-20 is a potent and orally active xanthine oxidase (XO) inhibitor with an IC50 of 1.7 nM. Xanthine oxidase-IN-20 exhibits outstanding serum uric acid (SUA)-lowering efficacy in both mouse and rat acute hyperuricemia models. Xanthine oxidase-IN-20 shows favorable safety profile. Xanthine oxidase-IN-20 can be used for hyperuricemia and gout research. | |||||||||||||||||||||
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