3072861-91-4
3072861-91-4
Chemical Structure
PROTAC IRAK3 degrader-2
- CAS 番号: 3072861-91-4
- Formula:C52H69N13O8
- Molecular Weight:1004.19
InChIKey: BOVIFRSWBWDSBT-UBCIQXRHSA-N
SMILES: CCOC(C1=C(N=C(N=C1)NC2=CN(N=C2)C)N[C@@H]3CC[C@@H](CC3)N4CCN(CC4)C([C@H]5CC[C@@H](CC5)C(N6CCC(CC6)CN7CCN(CC7)C8=CC9=C(C(N(C9=O)C%10CCC(NC%10=O)=O)=O)C=C8)=O)=O)=O
Biological Activity: PROTAC IRAK3 degrader-2 (Compound 17) is a IRAK3 PROTAC degrader with a DC50 ≤ 50 nM. It promotes ubiquitination and degradation of IRAK3, and is applicable to the research of immune diseases[1].
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PROTAC IRAK3 degrader-2 | PROTAC IRAK3 degrader-2 (Compound 17) is a IRAK3 PROTAC degrader with a DC50 ≤ 50 nM. It promotes ubiquitination and degradation of IRAK3, and is applicable to the research of immune diseases. | |||||||||||||||||||||
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References
Keywords
