3072863-05-6
Chemical Structure
E3 Ligase Ligand-linker Conjugate 226
- CAS No.: 3072863-05-6
- Formula:C31H39N5O7
- Molecular Weight:593.67
InChIKey: UOZAHSAFNXUFGI-FPCUACJBSA-N
SMILES: OC([C@H]1CC[C@@H](CC1)C(N2CCC(CC2)CN3CCN(CC3)C4=CC5=C(C(N(C5=O)C6CCC(NC6=O)=O)=O)C=C4)=O)=O
Biological Activity: E3 Ligase Ligand-linker Conjugate 226 is a synthetic E3 ligase ligand-linker conjugate that can be used to synthesize PROTACs, such as PROTAC IRAK3 degrader-2 (HY-181898). GXF-111 is a IRAK PROTAC degrader with anti-tumor activity[1].
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E3 Ligase Ligand-linker Conjugate 226 | E3 Ligase Ligand-linker Conjugate 226 is a synthetic E3 ligase ligand-linker conjugate that can be used to synthesize PROTACs, such as PROTAC IRAK3 degrader-2 (HY-181898). GXF-111 is a IRAK PROTAC degrader with anti-tumor activity. | |||||||||||||||||||||
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