3074495-82-9
3074495-82-9
Chemical Structure
FB49
- CAS No.: 3074495-82-9
- Formula:C17H18N2O6S
- Molecular Weight:378.40
InChIKey: SKJITVGQMCOZBC-LCYFTJDESA-N
SMILES: O=C(N(C(C)C(N1CCOCC1)=O)C/2=O)SC2=C/C3=CC=CC(O)=C3O
Biological Activity: FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM. FB49 inhibits the cell growth in human tumoral cells, but has no toxicity in human peripheral mononuclear cells. FB49 block cell cycle in G1 phase and to induce apoptosis as well as autophagy in medulloblastoma HD-MB03 treated cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FB49 | 98.38% | FB49 is a highly selective inhibitor of Bcl-2-associated athanogene 3 (BAG3), with the Ki of 45 μM. FB49 inhibits the cell growth in human tumoral cells, but has no toxicity in human peripheral mononuclear cells. FB49 block cell cycle in G1 phase and to induce apoptosis as well as autophagy in medulloblastoma HD-MB03 treated cells. | ||||||||||||||||||||
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Structural Analogs
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Similarity Score 0.51
HY-149644CB2R agonist 3 -
Similarity Score 0.50
HY-W838814ERK1/2 inhibitor 12 -
Similarity Score 0.49
HY-151352DHDPS-IN-1 -
Similarity Score 0.49
HY-168719PPARγ agonist 16 -
Similarity Score 0.49
HY-149645CB2 receptor antagonist 2 -
Similarity Score 0.49
HY-163646(Rac)-TZ3O -
Similarity Score 0.47
HY-120884InhA-IN-5 -
Similarity Score 0.46
HY-113592ERK-IN-4 -
Similarity Score 0.46
HY-164460AZD1897 -
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