3077585-25-9
Chemical Structure
KHKI-01215
- CAS No.: 3077585-25-9
- Formula:C24H26F3IN6O
- Molecular Weight:598.40
InChIKey: DYVNPOSCOSNLJH-UHFFFAOYSA-N
SMILES: FC(C1=CC(NC2=NC=C(I)C(OC3=CC=CC(N(C)C)=C3)=N2)=CC=C1N4CCN(C)CC4)(F)F
Biological Activity: KHKI-01215 is an inhibitor for NUAK2 with an IC50 of 0.052 μM. KHKI-01215 inhibits the proliferation of cancer cell SW480 with an IC50 of 3.16 μM, induces apoptosis in SW480. KHKI-01215 inhibits the YAP signaling pathway[1].
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KHKI-01215 | 98.78% | KHKI-01215 is an inhibitor for NUAK2 with an IC50 of 0.052 μM. KHKI-01215 inhibits the proliferation of cancer cell SW480 with an IC50 of 3.16 μM, induces apoptosis in SW480. KHKI-01215 inhibits the YAP signaling pathway. | ||||||||||||||||||||
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Keywords