3087853-45-7
3087853-45-7
Chemical Structure
PARP1-IN-53
- CAS No.: 3087853-45-7
- Formula:C22H19N5O3
- Molecular Weight:401.42
InChIKey: QWABSPLDVUYPFT-CMDGGOBGSA-N
SMILES: O=C1NC(/C=C/C(N2CCN(C3=CC=C(C#N)C=C3)CC2)=O)=NC4=C(O)C=CC=C41
Biological Activity: PARP1-IN-53 (Compound 328) is a quinazolinone derivative and PARP1 inhibitor with a PARP1 IC50 of 0.1 nM and selectivity over PARP2, which has a PARP2 IC50 of 23 nM.PARP1-IN-53 can be used for the research of cancer[1].
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PARP1-IN-53 | PARP1-IN-53 (Compound 328) is a quinazolinone derivative and PARP1 inhibitor with a PARP1 IC50 of 0.1 nM and selectivity over PARP2, which has a PARP2 IC50 of 23 nM.PARP1-IN-53 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
