PARP1-IN-53
PARP1-IN-53 (Compound 328) is a quinazolinone derivative and PARP1 inhibitor with a PARP1 IC50 of 0.1 nM and selectivity over PARP2, which has a PARP2 IC50 of 23 nM.PARP1-IN-53 can be used for the research of cancer.
For research use only. We do not sell to patients.
- CAS No.: 3087853-45-7
- Formula: C22H19N5O3
- Molecular Weight:401.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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PARP-1 0.1 nM (IC50) |
PARP-2 23 nM (IC50) |
Chemical Information
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CAS No. 3087853-45-7
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Molecular Weight 401.42
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Formula C22H19N5O3
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SMILES
O=C1NC(/C=C/C(N2CCN(C3=CC=C(C#N)C=C3)CC2)=O)=NC4=C(O)C=CC=C41
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)