3097646-96-0
3097646-96-0
Chemical Structure
4H-Chromen-4-one-o-carborane
- CAS No.: 3097646-96-0
- Formula:C11H16B10O2
- Molecular Weight:288.35
SMILES: O=C1C=2C=CC=CC2OC=C1C3456[BH]789[BH]%10%11%12[BH]%13%14%15[BH]%10%169[BH]%13%17%18[BH]%14%19%20[BH]%15%11%21[BH]%1276[BH]%21%195[CH]%17%204[BH]%16%1883
Biological Activity: 4H-Chromen-4-one-o-carborane is an estrogen receptor (ER) agonist, with an EC50 of 0.9 μM for ERα and an EC50 of 11.1 μM for ERβ. 4H-Chromen-4-one-o-carborane also acts as an inhibitor of COX-1 and COX-2, with an IC50 of 6.6 μM for COX-1 and an IC50 of 17.7 μM for COX-2[1].
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4H-Chromen-4-one-o-carborane | 4H-Chromen-4-one-o-carborane is an estrogen receptor (ER) agonist, with an EC50 of 0.9 μM for ERα and an EC50 of 11.1 μM for ERβ. 4H-Chromen-4-one-o-carborane also acts as an inhibitor of COX-1 and COX-2, with an IC50 of 6.6 μM for COX-1 and an IC50 of 17.7 μM for COX-2. | |||||||||||||||||||||
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