3104477-57-5
3104477-57-5
Chemical Structure
SLC6A19-IN-3
- CAS No.: 3104477-57-5
- Formula:C21H25ClN4O2
- Molecular Weight:400.90
InChIKey: DTYHHFDJBWNTKT-KFKAGJAMSA-N
SMILES: CNC(N1C[C@@H](C[C@H]2C[C@H]21)N(C3CC3)C(NCC#CC4=CC=CC(Cl)=C4)=O)=O
Biological Activity: SLC6A19-IN-3 (Compound 83-P1-P2) is a potent, selective and orally active SLC6A19 inhibitor with an IC50 of 28 nM. SLC6A19-IN-3 can block SLC6A19-mediated transmembrane transport of phenylalanine, reducing intestinal absorption of phenylalanine from food and renal tubular reabsorption of phenylalanine. SLC6A19-IN-3 can be used for the research of metabolic disease, such as phenylketonuria[1].
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SLC6A19-IN-3 | SLC6A19-IN-3 (Compound 83-P1-P2) is a potent, selective and orally active SLC6A19 inhibitor with an IC50 of 28 nM. SLC6A19-IN-3 can block SLC6A19-mediated transmembrane transport of phenylalanine, reducing intestinal absorption of phenylalanine from food and renal tubular reabsorption of phenylalanine. SLC6A19-IN-3 can be used for the research of metabolic disease, such as phenylketonuria. | |||||||||||||||||||||
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