3104986-47-9
Chemical Structure
DOTA-PEG5-azide
- No. CAS: 3104986-47-9
- Formula:C28H52N8O12
- Molecular Weight:692.76
IUPAC Name: 2,2',2''-(10-(20-azido-2-oxo-6,9,12,15,18-pentaoxa-3-azaicosyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetic acid
InChIKey: HCVDFVATJBFZPK-UHFFFAOYSA-N
SMILES: O=C(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(O)=O)NCCOCCOCCOCCOCCOCC[N-][N+]#N
Biological Activity: DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
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DOTA-PEG5-azide | 98.0% | DOTA-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DOTA-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | ||||||||||||||||||||
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Similarity Score 0.88
HY-140754Bromoacetamido-PEG5-DOTA -
Similarity Score 0.88
HY-W755033NH2-PEG4-DOTA -
Similarity Score 0.86
HY-164379DOTA-PEG4-alkyne -
Similarity Score 0.71
HY-W678394DOTA-Thiol -
Similarity Score 0.70
HY-164588NH2-PEG4-NODA-GA -
Similarity Score 0.70
HY-186088DOTA-tris(t-Bu)ester-PEG3-C2-amine -
Similarity Score 0.70
HY-W7177794-Aminobutyl-DOTA -
Similarity Score 0.69
HY-W539916Azido-mono-amide-DOTA -
Similarity Score 0.69
HY-W782078Butyne-DOTA -
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