3105410-45-2
3105410-45-2
Chemical Structure
TLR9 antagonist 1
- CAS No.: 3105410-45-2
- Formula:C28H33N5O
- Molecular Weight:455.59
IUPAC Name: 5-(5-(4-((2-methoxybenzyl)amino)butyl)hexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl)quinoline-8-carbonitrile
InChIKey: AHAZIWQQGKAYRI-UHFFFAOYSA-N
SMILES: N#CC1=C2N=CC=CC2=C(N3C(CN(CCCCNCC4=CC=CC=C4OC)C5)C5CC3)C=C1
Biological Activity: TLR9 antagonist 1 is a selective hTLR9 antagonist with an IC50 of 0.1 nM against hTLR9. TLR9 antagonist 1 exhibits favorable pharmacokinetic and pharmacodynamic properties. TLR9 antagonist 1 can be used in the research of systemic lupus erythematosus[1].
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TLR9 antagonist 1 | TLR9 antagonist 1 is a selective hTLR9 antagonist with an IC50 of 0.1 nM against hTLR9. TLR9 antagonist 1 exhibits favorable pharmacokinetic and pharmacodynamic properties. TLR9 antagonist 1 can be used in the research of systemic lupus erythematosus. | |||||||||||||||||||||
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