3105699-76-8
3105699-76-8
Chemical Structure
IMHDPA-4-OH
- CAS No.: 3105699-76-8
- Formula:C17H20N6O
- Molecular Weight:324.38
InChIKey: ORZYHABJRUDFCR-UFFVCSGVSA-N
SMILES: OC1=CC=CC2=C1C(/C=N/NC3=NC=NC(N(CC)CC)=C3)=CN2
Biological Activity: IMHDPA-4-OH is an mTORC1 inhibitor and autophagy inducer. IMHDPA-4-OH inhibits mTORC1 signaling and reduces p70S6K and p4EBP1 phosphorylation, thereby relieving the autophagy blockade. IMHDPA-4-OH interferes with cholesterol metabolism and induces cell cycle arrest at G0. IMHDPA-4-OH can be used for research on cervical cancer[1].
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IMHDPA-4-OH | IMHDPA-4-OH is an mTORC1 inhibitor and autophagy inducer. IMHDPA-4-OH inhibits mTORC1 signaling and reduces p70S6K and p4EBP1 phosphorylation, thereby relieving the autophagy blockade. IMHDPA-4-OH interferes with cholesterol metabolism and induces cell cycle arrest at G0. IMHDPA-4-OH can be used for research on cervical cancer. | |||||||||||||||||||||
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