3108486-39-8
3108486-39-8
Chemical Structure
P2X4 antagonist-4
- CAS No.: 3108486-39-8
- Formula:C27H22FN3O4S
- Molecular Weight:503.54
InChIKey: YEBHYBSHXPKIRM-UHFFFAOYSA-N
SMILES: O=S(CC1=CC=C(F)C=C1C)(NC2=CC=C(N(C(C3)=O)C4=CC=C5C=CC=CC5=C4NC3=O)C=C2)=O
Biological Activity: P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. P2X4 antagonist-4 blocks the ATP-induced NLRP3 inflammasome activation and release of IL-1β[1].
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P2X4 antagonist-4 | P2X4 antagonist-4 (compound 64) is a potent P2X4R antagonist with an IC50 value of 8 µM. P2X4 antagonist-4 blocks the ATP-induced NLRP3 inflammasome activation and release of IL-1β. | |||||||||||||||||||||
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References
Keywords
