3120534-54-2
3120534-54-2
Chemical Structure
SERT/5-HT-IN-1
- CAS. Nr.: 3120534-54-2
- Formula:C15H18N2S
- Molecular Weight:258.38
InChIKey: WNADBYWWPRYXMO-UHFFFAOYSA-N
SMILES: N1(C2=C(SC=C3)C3=CC=C2)CCC4(CNC4)CC1
Biological Activity: SERT/5-HT-IN-1 (compound D17) is an orally active and potent dual target inhibitor of SERT/5-HT3A (SERT IC50 = 1.5 nM, NET IC50 = 49 nM, DAT IC50 = 91 nM, 5-HT3A Ki = 12 nM). SERT/5-HT-IN-1 has an IC50 of 39 nM to 5-HT3A. SERT/5-HT-IN-1 has a lower risk of liver, kidney, and cardiac toxicity. SERT/5-HT-IN-1 can be used for research on depressive disorders[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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SERT/5-HT-IN-1 | 99.44% | SERT/5-HT-IN-1 (compound D17) is an orally active and potent dual target inhibitor of SERT/5-HT3A (SERT IC50 = 1.5 nM, NET IC50 = 49 nM, DAT IC50 = 91 nM, 5-HT3A Ki = 12 nM). SERT/5-HT-IN-1 has an IC50 of 39 nM to 5-HT3A. SERT/5-HT-IN-1 has a lower risk of liver, kidney, and cardiac toxicity. SERT/5-HT-IN-1 can be used for research on depressive disorders. | ||||||||||||||||||||
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