312306-89-1
Chemical Structure
Neuromedin U-25 (human)
- CAS No.: 312306-89-1
- Formula:C141H203N41O38
- Molecular Weight:3080.37
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: C([C@@H](NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CC=C(O)C=C3)NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]4N(C([C@@H](NC([C@@H](NC([C@H](CC5=CC=CC=C5)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC6=CC=CC=C6)N)=O)CCCNC(=N)N)=O)C(C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)CCC(N)=O)=O)CO)=O)CCC4)CC7=CC=CC=C7)=O)C)=O)CO)=O)CCC(N)=O)=O)CO)=O)CCCNC(=N)N)=O)=O)=O)=O)CC(C)C)=O)=O)CCCNC(=N)N)(=O)N8[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CCCNC(=N)N)=O)CCC8
Biological Activity: Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Neuromedin U-25 (human) | 99.05% | Neuromedin U-25 human is the active form of neuromedin U in human. Neuromedin U-25 human inhibits glucose-stimulated insulin secretion, which leads to early-onset obesity. Neuromedin U-25 serves as vasoconstrictor in human vascular beds. | ||||||||||||||||||||
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Similarity Score 0.89
HY-P4682Neuromedin U-25 (porcine) -
Similarity Score 0.82
HY-P10006Leumorphin, human -
Similarity Score 0.81
HY-P3629Dynorphin B 29 (pig) -
Similarity Score 0.80
HY-P1238Neuromedin U, rat -
Similarity Score 0.77
HY-P191526Rfa, Hypothalamic Peptide, human -
Similarity Score 0.76
HY-P2472Orphan GPCR SP9155 agonist P550 (mouse, rat) -
Similarity Score 0.75
HY-P3872Peptide B, bovine -
Similarity Score 0.74
HY-P4731Kisspeptin-54 (27-54) (human) -
Similarity Score 0.73
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HY-106323[Leu13]-Motilin -
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References
- [1]. Mitchell JD, et al., Expression and vasoconstrictor function of anorexigenic peptides neuromedin U-25 and S in the human cardiovascular system. Cardiovasc Res. 2009 Feb 1;81(2):353-61. [Content Brief]
- [2]. Alfa RW, et al., Suppression of insulin production and secretion by a decretin hormone. Cell Metab. 2015 Feb 3;21(2):323-334. [Content Brief]
