312622-77-8
Chemical Structure
VU0090157
- CAS No.: 312622-77-8
- Formula:C19H21N3O7
- Molecular Weight:403.39
IUPAC Name: cyclopentyl 1,6-dimethyl-4-(6-nitrobenzo[d][1,3]dioxol-5-yl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
InChIKey: GUFKDOZSNUQIAS-UHFFFAOYSA-N
SMILES: O=C(OC1CCCC1)C2=C(N(C(NC2C3=C(C=C4OCOC4=C3)[N+]([O-])=O)=O)C)C
Biological Activity: VU0090157 is a positive allosteric modulator (PAM) of the M1 muscarinic acetylcholine receptor (mAChR). VU0090157 increases the affinity of ACh by binding to the allosteric site. VU0090157 can be used in the study of schizophrenia and Alzheimer's disease[1].
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VU0090157 | VU0090157 is a positive allosteric modulator (PAM) of the M1 muscarinic acetylcholine receptor (mAChR). VU0090157 increases the affinity of ACh by binding to the allosteric site. VU0090157 can be used in the study of schizophrenia and Alzheimer's disease. | |||||||||||||||||||||
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Keywords