32385-11-8
Chemical Structure
Sisomicin
Synonym(s): Antibiotic 6640; Rickamicin
- CAS No.: 32385-11-8
- Formula:C19H37N5O7
- Molecular Weight:447.53
IUPAC Name: (2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-diamino-3-(((2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol
InChIKey: URWAJWIAIPFPJE-YFMIWBNJSA-N
SMILES: O[C@@H]([C@@H]1O[C@@]2([H])OC(CN)=CC[C@H]2N)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O
Biological Activity: Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria[1][2].
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Sisomicin | 99.98% | Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria. | ||||||||||||||||||||
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Sisomicin (Standard) | ≥98% | Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria. | ||||||||||||||||||||
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-
Similarity Score 0.86
HY-127054Netilmicin -
Similarity Score 0.79
HY-148286RGentamicin C1a (Standard) -
Similarity Score 0.77
HY-129480Vertilmicin -
Similarity Score 0.76
HY-N11857Gentamicin C2 -
Similarity Score 0.75
HY-B1915Micronomicin -
Similarity Score 0.74
HY-167256Gentamicin C1 -
Similarity Score 0.74
HY-N14514Gentamicin X2 -
Similarity Score 0.73
HY-133929Gentamicin B -
Similarity Score 0.72
HY-N151261-Deamino-1-hydroxygentamicin C1a -
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References
- [1]. Crowe CC, et al. Sisomicin: evaluation in vitro and comparison with gentamicin and tobramycin. Antimicrob Agents Chemother. 1973 Jan;3(1):24-8. [Content Brief]
- [2]. P Noone, et al. Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use. Drugs. 1984 Jun;27(6):548-78. [Content Brief]
