1. Micronomicin

Micronomicin  (Synonyms: Gentamicin C2b; Antibiotic XK-62-2; Sagamicin)

Cat. No.: HY-B1915 Purity: 95.16%
COA Handling Instructions

Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities.

For research use only. We do not sell to patients.

Micronomicin Chemical Structure

Micronomicin Chemical Structure

CAS No. : 52093-21-7

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This product is a controlled substance and not for sale in your territory.

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Description

Micronomicin (Gentamicin C2b) is an aminoglycoside antibiotic, with antibacterial and bactericidal activities[1].

IC50 & Target

bacteria[1]

In Vitro

Micronomicin shows a broad antibacterial spectrum against Gram positive and Gram negative bacteria[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

463.57

Formula

C20H41N5O7

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O[C@@H]([C@@H]1O[C@@]([C@@H](CC2)N)([H])O[C@@H]2CNC)[C@H]([C@@H](C[C@@H]1N)N)O[C@](OC[C@](C)(O)[C@@H]3NC)([H])[C@@H]3O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (539.29 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1572 mL 10.7859 mL 21.5717 mL
5 mM 0.4314 mL 2.1572 mL 4.3143 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (107.86 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1572 mL 10.7859 mL 21.5717 mL 53.9293 mL
5 mM 0.4314 mL 2.1572 mL 4.3143 mL 10.7859 mL
10 mM 0.2157 mL 1.0786 mL 2.1572 mL 5.3929 mL
15 mM 0.1438 mL 0.7191 mL 1.4381 mL 3.5953 mL
20 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.6965 mL
25 mM 0.0863 mL 0.4314 mL 0.8629 mL 2.1572 mL
30 mM 0.0719 mL 0.3595 mL 0.7191 mL 1.7976 mL
40 mM 0.0539 mL 0.2696 mL 0.5393 mL 1.3482 mL
50 mM 0.0431 mL 0.2157 mL 0.4314 mL 1.0786 mL
60 mM 0.0360 mL 0.1798 mL 0.3595 mL 0.8988 mL
80 mM 0.0270 mL 0.1348 mL 0.2696 mL 0.6741 mL
100 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.5393 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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