327056-22-4
327056-22-4
Chemical Structure
VU0285683
- CAS No.: 327056-22-4
- Formula:C14H7FN4O
- Molecular Weight:266.23
IUPAC Name: 3-fluoro-5-(3-(pyridin-2-yl)-1,2,4-oxadiazol-5-yl)benzonitrile
InChIKey: GELAFISMURFRCA-UHFFFAOYSA-N
SMILES: N#CC1=CC(C2=NC(C3=NC=CC=C3)=NO2)=CC(F)=C1
Biological Activity: VU0285683 is a selective mGluR5 positive allosteric modulator (PAM). VU0285683 has anxiolytic-like activity in rodent models for anxiety[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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VU0285683 | 99.76% | VU0285683 is a selective mGluR5 positive allosteric modulator (PAM). VU0285683 has anxiolytic-like activity in rodent models for anxiety. | ||||||||||||||||||||
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References
- [1]. Alice L Rodriguez, et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity. Mol Pharmacol. 2010 Dec;78(6):1105-23. [Content Brief]
