332117-28-9
332117-28-9
Chemical Structure
Chembridge-5861528
Synonym(s): TCS 5861528
- CAS No.: 332117-28-9
- Formula:C19H23N5O3
- Molecular Weight:369.42
IUPAC Name: N-(4-(sec-butyl)phenyl)-2-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)acetamide
InChIKey: ZUTUWJYMCADJHD-UHFFFAOYSA-N
SMILES: O=C1C2=C(N=CN2CC(NC3=CC=C(C(C)CC)C=C3)=O)N(C)C(N1C)=O
Biological Activity: Chembridge-5861528 (TCS 5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively. Chembridge-5861528 shows antihypersensitivity activities[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chembridge-5861528 | 99.12% | Chembridge-5861528 (TCS 5861528) is a potent TRPA1 channel antagonist that antagonizes similarly allyl isothiocyanate- and 4-HNE-evoked TRPA1 responses, with IC50 values of 14.3 μM and 18.7 μM, respectively. Chembridge-5861528 shows antihypersensitivity activities. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.90
HY-15064RHC-030031 (Standard) -
Similarity Score 0.70
HY-158149T-1-PMPA -
Similarity Score 0.65
HY-18988ETC-159 -
Similarity Score 0.64
HY-169520VEGFR/PDGFR-IN-1 -
Similarity Score 0.63
HY-W683885Dimabefylline -
Similarity Score 0.62
HY-B1505Acefylline -
Similarity Score 0.61
HY-U00344Theodrenaline -
Similarity Score 0.61
HY-124424VU0071063 -
Similarity Score 0.61
HY-107348REtofylline clofibrate (Standard) -
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