337972-47-1
Chemical Structure
FAUC 213
- CAS No.: 337972-47-1
- Formula:C18H19ClN4
- Molecular Weight:326.82
IUPAC Name: 2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)pyrazolo[1,5-a]pyridine
InChIKey: DTRXURJDKOYCCD-UHFFFAOYSA-N
SMILES: ClC(C=C1)=CC=C1N(CC2)CCN2CC3=NN4C=CC=CC4=C3
Biological Activity: FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. FAUC 213 has less activity on D2 and D3 receptors (Kis of 3.4 μM, 5.3 μM for hD2, hD3, respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic[1].
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FAUC 213 | 99.54% | FAUC 213 is an orally active and highly selective dopamine D4 receptor complete antagonist with a Ki of 2.2 nM for hD4.4. FAUC 213 has less activity on D2 and D3 receptors (Kis of 3.4 μM, 5.3 μM for hD2, hD3, respectively). FAUC 213 can cross the blood-brain barrier (BBB). FAUC 213 exhibits atypical antipsychotic characteristic. | ||||||||||||||||||||
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Keywords
