351520-91-7
Chemical Structure
2002-H20
- CAS No.: 351520-91-7
- Formula:C20H15N3O3
- Molecular Weight:345.35
IUPAC Name: 4-amino-N-(3-(benzo[d]oxazol-2-yl)-4-hydroxyphenyl)benzamide
InChIKey: NVVIQGMTHCUMFT-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C=C1)N)NC2=CC=C(C(C3=NC4=CC=CC=C4O3)=C2)O
Biological Activity: 2002-H20 is an inhibitor of Aβ42-induced cytotoxicity, with the activity of reducing the cytotoxicity of Alzheimer's disease Aβ peptide by binding to it. 2002-H20 protects cells and reduces Aβ toxicity by promoting fibril formation, possibly by accelerating Aβ aggregation. The screening method of 2002-H20 effectively identifies compounds that reduce Aβ toxicity and presents potential inhibitory leads[1].
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2002-H20 | 2002-H20 is an inhibitor of Aβ42-induced cytotoxicity, with the activity of reducing the cytotoxicity of Alzheimer's disease Aβ peptide by binding to it. 2002-H20 protects cells and reduces Aβ toxicity by promoting fibril formation, possibly by accelerating Aβ aggregation. The screening method of 2002-H20 effectively identifies compounds that reduce Aβ toxicity and presents potential inhibitory leads. | |||||||||||||||||||||
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