362-43-6
Chemical Structure
2',3'-O-Isopropylideneuridine
Synonym(s): 2',3'-O-Isopropylidene-D-uridine
- CAS No.: 362-43-6
- Formula:C12H16N2O6
- Molecular Weight:284.27
IUPAC Name: 1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: GFDUSNQQMOENLR-PEBGCTIMSA-N
SMILES: OC[C@@H]1[C@@H](OC(C)(C)O2)[C@@H]2[C@H](N3C(NC(C=C3)=O)=O)O1
Biological Activity: 2',3'-O-Isopropylideneuridine is a uridine nucleoside analog that can be used as a precursor in organic synthesis. 2',3'-O-Isopropylideneuridine itself has no significant biological activity, but it can be used to synthesize derivatives with significant anti-HIV-1 activity and central nervous system depressant and hypnotic activities. 2',3'-O-Isopropylideneuridine can be used in research on viral infections and neurological diseases[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2',3'-O-Isopropylideneuridine | 99.86% | 2',3'-O-Isopropylideneuridine is a uridine nucleoside analog that can be used as a precursor in organic synthesis. 2',3'-O-Isopropylideneuridine itself has no significant biological activity, but it can be used to synthesize derivatives with significant anti-HIV-1 activity and central nervous system depressant and hypnotic activities. 2',3'-O-Isopropylideneuridine can be used in research on viral infections and neurological diseases. | ||||||||||||||||||||
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Similarity Score 0.83
HY-1542892’,3’-Isopropylidene-5-hydroxyuridine -
Similarity Score 0.81
HY-1418842',3'-O-Isopropylidenecytidine -
Similarity Score 0.80
HY-W5520675-(Hydroxymethyl)-2′,3′-O-(1-methylethylidene)uridine -
Similarity Score 0.78
HY-W5563012′,3′-O-Isopropylideneisocytidine -
Similarity Score 0.75
HY-W011824R2′-O-Methyluridine (Standard) -
Similarity Score 0.75
HY-W4125463’-O-Methyluridine -
Similarity Score 0.75
HY-1526651-(β-D-Xylofuranosyl)uracil -
Similarity Score 0.75
HY-B1449S1Uridine-13C -
Similarity Score 0.75
HY-N6652R1-beta-D-Arabinofuranosyluracil (Standard) -
Explore the MedChemAI to find more analogs
References
- [1]. Glumakova K, et al. Nucleoside Analog 2',3'-Isopropylidene-5-Iodouridine as Novel Efficient Inhibitor of HIV-1. Pharmaceutics. 2023 Sep 27;15(10):2389. [Content Brief]
- [2]. Katti SK, et al. The structure of 2',3'-O-isopropylideneuridine. Acta Crystallogr B. 1981;37:407-10.
- [3]. Yao CS, et al. Synthesis and central nervous system depressant effects of N3-substituted 2',3'-O-isopropylideneuridines. Chem Pharm Bull (Tokyo).
