363-03-1
363-03-1
Chemical Structure
Phenylquinone
Synonym(s): 2-Phenylbenzoquinone
- CAS No.: 363-03-1
- Formula:C12H8O2
- Molecular Weight:184.19
IUPAC Name: [1,1'-biphenyl]-2,5-dione
InChIKey: RLQZIECDMISZHS-UHFFFAOYSA-N
SMILES: C1=CC=C(C=C1)C2=CC(=O)C=CC2=O
Biological Activity: Phenylquinone (2-Phenylbenzoquinone) causes pain and induces writhing in mice, and is often used in experiments to test the effectiveness of analgesics or agent that can suppress or relieve pain[1][2].
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Phenylquinone | 97.26% | Phenylquinone (2-Phenylbenzoquinone) causes pain and induces writhing in mice, and is often used in experiments to test the effectiveness of analgesics or agent that can suppress or relieve pain. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.81
HY-W0154901,4-Naphthoquinone -
Similarity Score 0.75
HY-B0332RMenadione (Standard) -
Similarity Score 0.74
HY-W5859436-Methyl-1,4-naphthoquinone -
Similarity Score 0.73
HY-W269306Bonaphthone -
Similarity Score 0.71
HY-N3968Goniothalamin -
Similarity Score 0.69
HY-N6611Chimaphilin -
Similarity Score 0.69
HY-I07171-Acetylnaphthalene -
Similarity Score 0.69
HY-18570R1-Naphthaleneacetic acid (Standard) -
Similarity Score 0.69
HY-196991-Naphthylacetamide -
Explore the MedChemAI to find more analogs
References
- [1]. TABER RI, et al. INHIBITION OF PHENYLQUINONE-INDUCED WRITHING BY NARCOTIC ANTAGONISTS. Nature. 1964 Oct 10;204:189-90. [Content Brief]
- [2]. Dewey WL, et al. The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. J Pharmacol Exp Ther. 1970 Nov;175(2):435-42. [Content Brief]
