365565-02-2
Chemical Structure
PGP-4008
- CAS. Nr.: 365565-02-2
- Formula:C26H23N3O
- Molecular Weight:393.48
IUPAC Name: N-(1-benzyl-2,3-dihydro-1H-pyrrolo[2,3-b]quinolin-4-yl)-2-phenylacetamide
InChIKey: HVIAKQBMYMKWII-UHFFFAOYSA-N
SMILES: O=C(CC1=CC=CC=C1)NC2=C3C(N(CC3)CC4=CC=CC=C4)=NC5=CC=CC=C25
Biological Activity: PGP-4008 is a specific P-glycoprotein (Pgp) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple agent resistance (MDR) solid tumor model when given in combination with Doxorubicin[1].
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PGP-4008 | 99.26% | PGP-4008 is a specific P-glycoprotein (Pgp) inhibitor. PGP-4008 inhibits tumor growth in a murine syngeneic Pgp-mediated multiple agent resistance (MDR) solid tumor model when given in combination with Doxorubicin. | ||||||||||||||||||||
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Keywords