36840-10-5
36840-10-5
Chemical Structure
LPA2 antagonist 2
- CAS No.: 36840-10-5
- Formula:C20H16N2O6
- Molecular Weight:380.35
IUPAC Name: (2E,2'E)-4,4'-([1,1'-biphenyl]-4,4'-diylbis(azanediyl))bis(4-oxobut-2-enoic acid)
InChIKey: FTLRWRKPUWMOMS-WGDLNXRISA-N
SMILES: O=C(O)/C=C/C(NC1=CC=C(C2=CC=C(NC(/C=C/C(O)=O)=O)C=C2)C=C1)=O
Biological Activity: LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LPA2 antagonist 2 | 95.0% | LPA2 antagonist 2 (H2L 5226501) is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 21.1 nM. LPA2 antagonist 2 is >480-fold more selective than LPA3 (IC50 of 13.85 μM). | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-107616H2L5186303 -
Similarity Score 0.63
![(2E,2'E)-3,3'-([1,1'-Biphenyl]-4,4'-diyl)diacrylic acid Chemical Structure](//file.medchemexpress.com/product_pic/hy-w456495.gif)
HY-W456495(2E,2'E)-3,3'-([1,1'-Biphenyl]-4,4'-diyl)diacrylic acid -
Similarity Score 0.60
HY-W1121684,4'-(Carbonylbis(azanediyl))dibenzoicacid -
Similarity Score 0.57
HY-152552α-Synuclein inhibitor 8 -
Similarity Score 0.57
HY-135323Acetaminophen impurity 1 -
Similarity Score 0.57
HY-135658hDHODH-IN-1 -
Similarity Score 0.57
![1-([1,1'-Biphenyl]-4-yl)urea Chemical Structure](//file.medchemexpress.com/product_pic/hy-w198426.gif)
HY-W1984261-([1,1'-Biphenyl]-4-yl)urea -
Similarity Score 0.57
HY-12346FH1 -
Similarity Score 0.56
HY-W613379Biphenyl-4,4'-diacetic acid -
Explore the MedChemAI to find more analogs
![(2E,2'E)-3,3'-([1,1'-Biphenyl]-4,4'-diyl)diacrylic acid Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w456495.gif)
![1-([1,1'-Biphenyl]-4-yl)urea Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w198426.gif)
