3785-24-8
Chemical Structure
Nepodin
Synonym(s): Musizin
- CAS No.: 3785-24-8
- Formula:C13H12O3
- Molecular Weight:216.23
IUPAC Name: 1-(1,8-dihydroxy-3-methylnaphthalen-2-yl)ethan-1-one
InChIKey: DMLHPCALHMPJHS-UHFFFAOYSA-N
SMILES: CC(C1=C(C)C=C2C=CC=C(O)C2=C1O)=O
Biological Activity: Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus[1].Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK[2].Nepodin (Musizin) has antidiabetic and antimalarial activities.
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Nepodin | 97.46% | Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities. | ||||||||||||||||||||
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Nepodin (Standard) | ≥98% | Nepodin (Standard) is the analytical standard of Nepodin. This product is intended for research and analytical applications. Nepodin (Musizin) is a quinone oxidoreductase (PfNDH2) inhibitor isolate from Rumex crispus.Nepodin (Musizin) stimulates the translocation of GLUT4 to the plasma membrane by activation of AMPK.Nepodin (Musizin) has antidiabetic and antimalarial activities. | ||||||||||||||||||||
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- [1]. Lee KH, et al. Antimalarial activity of nepodin isolated from Rumex crispus. Arch Pharm Res. 2013 Apr;36(4):430-5. [Content Brief]
- [2]. Ha BG, et al. Antidiabetic effect of nepodin, a component of Rumex roots, and its modes of action in vitro and in vivo. Biofactors. 2014 Jul-Aug;40(4):436-47. [Content Brief]
Keywords