3934-02-9
3934-02-9
Chemical Structure
Dimebutic acid sodium
Synonym(s): NSC-16045 sodium; NSC-741804 sodium
- CAS No.: 3934-02-9
- Formula:C6H11NaO2
- Molecular Weight:138.14
InChIKey: OOPXYEYPPHJHSE-UHFFFAOYSA-M
SMILES: CCC(C)(C(O[Na])=O)C
Biological Activity: Dimebutic acid sodium is an orally active short-chain fatty acid. Dimebutic acid sodium stimulates fetal globin production and alters the balance of Bcl family proteins. Dimebutic acid sodium prolongs red blood cell survival. Dimebutic acid sodium exhibits toxicity in rats. Dimebutic acid sodium can be used in the study of β-thalassemia and sickle cell disease[1][2].
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Dimebutic acid sodium | Dimebutic acid sodium is an orally active short-chain fatty acid. Dimebutic acid sodium stimulates fetal globin production and alters the balance of Bcl family proteins. Dimebutic acid sodium prolongs red blood cell survival. Dimebutic acid sodium exhibits toxicity in rats. Dimebutic acid sodium can be used in the study of β-thalassemia and sickle cell disease. | |||||||||||||||||||||
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References
- [1]. Parise RA, et al. Liquid chromatography-mass spectrometric assay for quantitation of the short-chain fatty acid, 2,2-dimethylbutyrate (NSC 741804), in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Feb 1;862(1-2):168-74. [Content Brief]
- [2]. Terse PS, et al. Short-term toxicity study of ST-20 (NSC-741804) by oral gavage in Sprague-Dawley rats. Toxicol Pathol. 2011 Jun;39(4):614-22. [Content Brief]
Keywords
