396129-53-6
396129-53-6
Chemical Structure
LY-364947
Synonym(s): HTS466284
- CAS No.: 396129-53-6
- Formula:C17H12N4
- Molecular Weight:272.30
IUPAC Name: 4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)quinoline
InChIKey: IBCXZJCWDGCXQT-UHFFFAOYSA-N
SMILES: C1(C2=CNN=C2C3=NC=CC=C3)=CC=NC4=CC=CC=C14
Biological Activity: LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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LY-364947 | 99.23% | LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM, and exhibits 7-fold selectivity over TGFβR-II. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.82
HY-78349A 77-01 -
Similarity Score 0.71
HY-10327RGW-6604 (Standard) -
Similarity Score 0.64
HY-W684904LY550410 -
Similarity Score 0.63
HY-118810BIO-013077-01 -
Similarity Score 0.60
HY-W1124754'-(4-Quinolyl)-2,2':6',2"-terpyridine -
Similarity Score 0.59
HY-13012RRepSox (Standard) -
Similarity Score 0.59
HY-W707119RepSox hydrochloride -
Similarity Score 0.57
HY-17661Depiperazine-DM3189 -
Similarity Score 0.55
![4-([3,2':6',3''-Terpyridin]-4'-yl)quinoline Chemical Structure](//file.medchemexpress.com/product_pic/hy-w112501.gif)
HY-W1125014-([3,2':6',3''-Terpyridin]-4'-yl)quinoline -
Explore the MedChemAI to find more analogs
![4-([3,2':6',3''-Terpyridin]-4'-yl)quinoline Chemical Structure](http://file.medchemexpress.com/product_pic/hy-w112501.gif)
