403520-23-0
403520-23-0
Chemical Structure
VPC12249
- CAS No.: 403520-23-0
- Formula:C34H52NO6P
- Molecular Weight:601.75
IUPAC Name: (S)-3-(4-(benzyloxy)phenyl)-2-oleamidopropyl dihydrogen phosphate
InChIKey: NJLPYJKKKSBCSK-WDCKUFQWSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(N[C@@H](CC1=CC=C(OCC2=CC=CC=C2)C=C1)COP(O)(O)=O)=O
Biological Activity: VPC12249 is a competitive dual LPA1/LPA3 antagonist with Ki values of 137nM and 428 nM, respectively. VPC12249 inhibits calcium mobilization in HEK293T cells with a Ki value of ~130 nM. VPC12249 is promising for research of ovarian cancer and hypertensive diseases[1].
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VPC12249 | VPC12249 is a competitive dual LPA1/LPA3 antagonist with Ki values of 137nM and 428 nM, respectively. VPC12249 inhibits calcium mobilization in HEK293T cells with a Ki value of ~130 nM. VPC12249 is promising for research of ovarian cancer and hypertensive diseases. | |||||||||||||||||||||
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References
Keywords
