40437-72-7
Chemical Structure
Kaempferol-3-O-glucorhamnoside
- CAS No.: 40437-72-7
- Formula:C27H30O15
- Molecular Weight:594.52
IUPAC Name: 3-(((2S,3R,4R,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
InChIKey: OHOBPOYHROOXEI-OVNVQJKQSA-N
SMILES: C[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](CO)O[C@H]2OC3=C(C4=CC=C(O)C=C4)OC5=CC(O)=CC(O)=C5C3=O)O1
Biological Activity: Kaempferol-3-O-glucorhamnoside is a flavonoid compound. Kaempferol-3-O-glucorhamnoside can be extracted from T. chinense Turcz. Kaempferol-3-O-glucorhamnoside inhibits the phosphorylation of NF-κB and MAPK kinases. Kaempferol-3-O-glucorhamnoside suppresses the expression of cytokines (TNF-α, IL-6, IL-1β and PGE2) and reduces ROS levels. Kaempferol-3-O-glucorhamnoside ameliorates pulmonary edema and alleviates oxidative stress in the lungs and cells of mice exposed to Klebsiella pneumoniae. Kaempferol-3-O-glucorhamnoside possesses anti-inflammatory properties. Kaempferol-3-O-glucorhamnoside can be used in studies related to Klebsiella pneumoniae infection (pneumonia)[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Kaempferol-3-O-glucorhamnoside | 99.64% | Kaempferol-3-O-glucorhamnoside is a flavonoid compound. Kaempferol-3-O-glucorhamnoside can be extracted from T. chinense Turcz. Kaempferol-3-O-glucorhamnoside inhibits the phosphorylation of NF-κB and MAPK kinases. Kaempferol-3-O-glucorhamnoside suppresses the expression of cytokines (TNF-α, IL-6, IL-1β and PGE2) and reduces ROS levels. Kaempferol-3-O-glucorhamnoside ameliorates pulmonary edema and alleviates oxidative stress in the lungs and cells of mice exposed to Klebsiella pneumoniae. Kaempferol-3-O-glucorhamnoside possesses anti-inflammatory properties. Kaempferol-3-O-glucorhamnoside can be used in studies related to Klebsiella pneumoniae infection (pneumonia). | ||||||||||||||||||||
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References
- [1]. Sun Z, et al. Kaempferol-3-O-glucorhamnoside inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo. Toxicology and applied pharmacology. 2019 Feb 01;364:22-28. [Content Brief]
- [2]. Chen M, et al. Kaempferol and atherosclerosis: From mechanism to medicine. Critical reviews in food science and nutrition. 2024;64(8):2157-2175. [Content Brief]
- [3]. Wang L, et al. Integrative study of Anchusa italica Retz flower's microstructure and chemical composition. Scientific reports. 2025 Feb 21;15(1):6366. [Content Brief]
